Article
Discs large 5, an Essential Gene in Drosophila, Regulates Egg Chamber Organization.
G3 (Bethesda, Md.) - 19 Mar 2015
Reilly Eve, Changela Neha, Naryshkina Tatyana, Deshpande Girish, Steward Ruth
Abstract excerpt
Discs large 5 (Dlg5) is a member of the MAGUK family of proteins that typically serve as molecular scaffolds and mediate signaling complex formation and localization. In vertebrates, Dlg5 has been shown to be responsible for polarization of neural progenitors and to associate with Rab11-positive vesicles in epithelial cells. In Drosophila, however, the function of Dlg5 is not well-documented. We have identified...
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