Article
Eyes closed, a Drosophila p47 homolog, is essential for photoreceptor morphogenesis.
Development (Cambridge, England) - 1 Jan 2002
Sang Tzu-Kang, Ready Donald F
Abstract excerpt
Starting with a mutation impacting photoreceptor morphogenesis, we identify here a Drosophila gene, eyes closed (eyc), as a fly homolog of p47, a protein co-factor of the p97 ATPase implicated in membrane fusion. Temporal misexpression of Eyc during rhabdomere extension early in pupal life results in inappropriate retention of normally transient adhesions between developing rhabdomeres. Later Eyc misexpression...
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