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Article

The conserved c2 domain protein lethal (2) giant discs regulates protein trafficking in Drosophila.

Developmental cell - 1 Nov 2006

Gallagher Ciara M, Knoblich Juergen A

Abstract excerpt

Drosophila sensory organ precursor (SOP) cells undergo several rounds of asymmetric cell division to generate the four different cell types that make up external sensory organs. Establishment of different fates among daughter cells of the SOP relies on differential regulation of the Notch pathway. Here, we identify the protein Lethal (2) giant discs (Lgd) as a critical regulator of Notch signaling in the SOP...

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Identifiers

PMID: 17084357
DOI: 10.1016/j.devcel.2006.09.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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