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Article

A novel pseudoknot element is essential for the action of a yeast telomerase.

Genes & development - 15 Jul 2003

Tzfati Yehuda, Knight Zachary, Roy Jagoree, Blackburn Elizabeth H

Abstract excerpt

Telomerase contains an essential RNA, which includes the template sequence copied by the reverse transcription action of telomerase into telomeric DNA. Using phylogenetic comparison, we identified seven conserved sequences in telomerase RNAs from Kluyveromyces budding yeasts. We show that two of these sequences, CS3 and CS4, are essential for normal telomerase function and can base-pair to form a putative...

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Identifiers

PMID: 12832393
DOI: 10.1101/gad.1099403
PMCID: PMC196185

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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