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Article

Yeast telomerase is specialized for C/A-rich RNA templates.

Nucleic acids research - 15 Mar 2003

Förstemann Klaus, Zaug Arthur J, Cech Thomas R, Lingner Joachim

Abstract excerpt

Telomeres, the protective caps of eukaryotic chromosomes, are maintained by the enzyme telomerase. This telomere-specific reverse transcriptase (RT) uses a small region of its RNA subunit as template to synthesize telomeric DNA, which is generally G/T rich in the strand that contains the 3' end. To further our understanding of why telomeres are usually G/T rich, we screened Saccharomyces cerevisiae telomerase RNA...

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Identifiers

PMID: 12626706
DOI: 10.1093/nar/gkg261
PMCID: PMC152863

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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