Article
Association of polymorphisms in the promoter region of the PNMT gene with essential hypertension in African Americans but not in whites.
American journal of hypertension - 1 Oct 2003
Cui Jing, Zhou Xiaofeng, Chazaro Irmarie, DeStefano Anita L, Manolis Athanasios J, Baldwin Clinton T, Gavras Haralambos
Abstract excerpt
BACKGROUND: Several studies have indicated that a region on human chromosome 17 may influence blood pressure. Our group reported positive linkage for hypertension to the region on human chromosome 17, between D17S1814 and D17S800 in white sibling pairs. In this study, we further investigated this result by examining the phenylethanolamine N-methyltransferase (PNMT) gene, which is located at 17q21 within the...
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