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Article

Association of a polymorphism of the angiotensin I-converting enzyme gene with essential hypertension.

Biochemical and biophysical research communications - 15 Apr 1992

Zee R Y, Lou Y K, Griffiths L R, Morris B J

Abstract excerpt

Angiotensin I-converting enzyme (ACE) is responsible for production of angiotensin II and breakdown of kinins, leading to increased blood pressure (BP). Furthermore, ACE inhibitors are effective antihypertensive agents. A 287 bp insertion/deletion polymorphism in intron 16 of the ACE gene (ACE) was examined by PCR in a cross-sectional study of 80 hypertensive (HT) and 93 normotensive (NT) subjects whose parents...

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Source

Identifiers

PMID: 1314601
DOI: 10.1016/0006-291x(92)91150-o

Genes

ACE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Association of a polymorphism of the angiotensin I-converting enzyme gene with essential hypertension.PMID 1314601Read ↗

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Association of angiotensin II type 1 receptor gene polymorphism with essential hypertension.Semantic proximity Read ↗

Association of variants in critical core promoter element of angiotensinogen gene with increased risk of essential hypertension in Japanese.Semantic proximity Read ↗

Estimation of risk and interaction of single nucleotide polymorphisms at angiotensinogen locus causing susceptibility to essential hypertension: a case control study.Semantic proximity Read ↗

Association of angiotensinogen gene polymorphisms with essential hypertension in African-Americans and Caucasians.Semantic proximity Read ↗

Chromosome 17 and the inducible nitric oxide synthase gene in human essential hypertension.Semantic proximity Read ↗

Angiotensin-converting enzyme gene polymorphism and its association with essential hypertension in a Tibetan population.Semantic proximity Read ↗

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