Article
Genetic variants of WNK4 in whites and African Americans with hypertension.
Hypertension (Dallas, Tex. : 1979) - 1 Jun 2003
Erlich Porat M, Cui Jing, Chazaro Irmarie, Farrer Lindsay A, Baldwin Clinton T, Gavras Haralambos, DeStefano Anita L
Abstract excerpt
Human chromosome 17q has been implicated to contain a gene that influences hypertension susceptibility. This region contains the WNK4 gene that causes the mendelian disorder pseudohypoaldosteronism type II, characterized by high potassium levels and hypertension. The goal of this study was to identify genetic variants in all exons of WNK4 in hypertensive individuals and to examine the association of these...
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