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Article

Association of APP gene polymorphisms and promoter methylation with essential hypertension in Guizhou: a case-control study.

Human genomics - 20 Mar 2023

Li Ruichao, Song Juhui, Zhao Ansu, Diao Xiaoyan, Zhang Ting, Qi Xiaolan, Guan Zhizhong, An Yu, Ren Lingyan, Wang Chanjuan, He Yan

Abstract excerpt

BACKGROUND: Single-nucleotide polymorphisms (SNPs) and DNA methylation are crucial regulators of essential hypertension (EH). Amyloid precursor protein (APP) mutations are implicated in hypertension development. Nonetheless, studies on the association of APP gene polymorphism and promoter methylation with hypertension are limited. Therefore, this case-control aims to evaluate the genetic association of APP gene...

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Share to Amyloid beta-Protein Precursor
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36941702
DOI: 10.1186/s40246-023-00462-y
PMCID: PMC10026478

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