Article
Phenylethanolamine N-methyltransferase gene promoter haplotypes and risk of essential hypertension.
American journal of hypertension - 1 Nov 2011
Huang Cheng, Zhang Saidan, Hu Ke, Ma Qilin, Yang Tianlun
Abstract excerpt
BACKGROUND: Phenylethanolamine N-methyltransferase gene (PNMT) catalyzes the synthesis of epinephrine and plays an important role in regulating cardiovascular function. Genetic variation in the PNMT promoter is reportedly associated with the risk of essential hypertension in certain population. METHODS: In the present study, we explored the association of two common PNMT promoter single-nucleotide polymorphisms...
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