Article
Human chromosome 17 in essential hypertension.
Annals of human genetics - 1 Mar 2003
Knight J, Munroe P B, Pembroke J C, Caulfield M J
Abstract excerpt
Hypertension affects up to 30% of the adult population in Western societies and is a major risk factor for kidney disease, stroke and coronary heart disease. It is a complex trait thought to be influenced by a number of genes and environmental factors, although the precise aetiology remains unknown at this time. A number of methods have been successfully used to identify mutations that cause Mendelian traits and...
Topics
- Animals
- Blood Pressure
- Chromosome Mapping
- Chromosomes, Human, Pair 17
- Disease Models, Animal
- Genetic Linkage
- Genetic Markers
- Humans
- Hypertension
- Mice
- Peptidyl-Dipeptidase A
- Phenotype
- Pseudohypoaldosteronism
- Quantitative Trait Loci
- Rats
- Rats, Inbred SHR
