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Article

Functional Polymorphism rs13306560 of the MTHFR Gene Is Associated With Essential Hypertension in a Mexican-Mestizo Population.

Circulation. Cardiovascular genetics - 1 Aug 2015

Pérez-Razo Juan Carlos, Cano-Martínez Luis Javier, Vargas Alarcón Gilberto, Canizales-Quinteros Samuel, Martínez-Rodríguez Nancy, Canto Patricia, Roque-Ramírez Bladimir, Palma-Flores Carlos, Esteban-Martínez Rosa, López-Hernández Luz Berenice, Rojano-Mejía David, Coral-Vázquez Ramón M

Abstract excerpt

BACKGROUND: Polymorphisms of methylenetetrahydrofolate reductase (MTHFR) have been associated with diastolic blood pressure, hypertension, and other cardiovascular diseases; however, results of these studies are still controversial. In this study, we sought to determine whether 2 functional variants (rs1801133 and rs13306560) within the MTHFR are associated with hypertension in Mexican-Mestizos. METHODS AND...

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Source

Identifiers

PMID: 26022245
DOI: 10.1161/CIRCGENETICS.114.000942

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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