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Article

Human phenylethanolamine N-methyltransferase pharmacogenomics: gene re-sequencing and functional genomics.

Journal of neurochemistry - 1 Dec 2005

Ji Yuan, Salavaggione Oreste E, Wang Liewei, Adjei Araba A, Eckloff Bruce, Wieben Eric D, Weinshilboum Richard M

Abstract excerpt

Phenylethanolamine N-methyltransferase (PNMT, EC2.1.1.28) catalyzes the N-methylation of norepinephrine to form epinephrine. As a step toward understanding the possible contribution of inheritance to individual variation in PNMT-catalyzed epinephrine formation, we 're-sequenced' the entire human PNMT gene, including the three exons, the introns and approximately 1 kb of the 5'-flanking region (5'-FR), using DNA...

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Source

Identifiers

PMID: 16277617
DOI: 10.1111/j.1471-4159.2005.03453.x

Genes

PNMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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