Article
Timing of establishment of paternal methylation imprints in the mouse.
Genomics - 1 Dec 2004
Li Jing-Yu, Lees-Murdock Diane J, Xu Guo-Liang, Walsh Colum P
Abstract excerpt
Imprinted genes are characterized by predominant expression from one parental allele and differential DNA methylation. Few imprinted genes have been found to acquire a methylation mark in the male germ line, however, and only one of these, H19, has been studied in detail. We examined methylation of the Rasgrf1 and Gtl2 differentially methylated regions (DMR) to determine whether methylation is erased in male germ...
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