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Article

Aurora-A kinase is essential for bipolar spindle formation and early development.

Molecular and cellular biology - 1 Feb 2009

Cowley Dale O, Rivera-Pérez Jaime A, Schliekelman Mark, He Yizhou Joseph, Oliver Trudy G, Lu Lucy, O'Quinn Ryan, Salmon E D, Magnuson Terry, Van Dyke Terry

Abstract excerpt

Aurora-A is a conserved kinase implicated in mitotic regulation and carcinogenesis. Aurora-A was previously implicated in mitotic entry and spindle assembly, although contradictory results prevented a clear understanding of the roles of Aurora-A in mammals. We developed a conditional null mutatio...

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Identifiers

PMID: 19075002
DOI: 10.1128/MCB.01062-08
PMCID: PMC2643803

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19075002-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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