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Article

Aurora-C kinase deficiency causes cytokinesis failure in meiosis I and production of large polyploid oocytes in mice.

Molecular biology of the cell - 15 Jul 2010

Yang Kuo-Tai, Li Shu-Kuei, Chang Chih-Chieh, Tang Chieh-Ju C, Lin Yi-Nan, Lee Sheng-Chung, Tang Tang K

Abstract excerpt

We previously isolated Aurora-C/Aie1 in a screen for kinases expressed in mouse sperm and eggs. Here, we show the localization of endogenous Aurora-C and examine its roles during female mouse meiosis. Aurora-C was detected at the centromeres and along the chromosome arms in prometaphase I-metapha...

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Identifiers

PMID: 20484572
DOI: 10.1091/mbc.e10-02-0170
PMCID: PMC2903667

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20484572-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Aurora-C kinase deficiency causes cytokinesis failure in meiosis I and production of large polyploid oocytes in mice.PMID 20484572Read ↗

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