Article
Role of DNA mismatch repair genetic polymorphisms in the risk of childhood acute lymphoblastic leukaemia.
British journal of haematology - 1 Oct 2003
Mathonnet Géraldine, Krajinovic Maja, Labuda Damian, Sinnett Daniel
Abstract excerpt
Acute lymphoblastic leukaemia (ALL) is the most common childhood cancer. Genetic variants in the coding regions of the mismatch repair genes MLH1 (Ile-219Val) and MSH3 (Arg-940Glu and Thr-1036Ala) could contribute to an individual's susceptibility as modifiers in leukaemogenesis. To investigate t...
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