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Article

MLH1 polymorphisms and cancer risk: a meta-analysis based on 33 case-control studies.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2012

Xu Jia-Li, Yin Zhi-Qiang, Huang Ming-De, Wang Xie-Feng, Gao Wen, Liu Ling-Xiang, Wang Rong-Sheng, Huang Pu-Wen, Yin Yong-Mei, Liu Ping, Shu Yong-Qian

Abstract excerpt

OBJECTIVE: Cumulative evidence suggests that MLH1, the key component in the mismatch pathway, plays an important role in human cancers. Two potential functional polymorphisms (-93G>A and I219V) of MLH1 have been implicated in cancer risk. The aim of this meta-analysis was to summarize the evidence for associations. METHODS: Eligible studies were identified by searching the electronic literature PubMed,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22631669
DOI: 10.7314/apjcp.2012.13.3.901

Genes

MLH1

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