Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Xenobiotic and folate pathway gene polymorphisms and risk of childhood acute lymphoblastic leukaemia in Javanese children.

Hematological oncology - 1 Sept 2011

Chan Jason Yong-Sheng, Ugrasena Dewa G, Lum Danny Wai-Kiong, Lu Yi, Yeoh Allen Eng-Juh

Abstract excerpt

Xenobiotic and folate metabolic pathways are important for the maintenance of genetic stability and may influence susceptibility to the development of childhood acute lymphoblastic leukaemia (ALL). In this study, we investigated 10 polymorphisms in 6 genes (GSTM1-present/null, GSTT1-present/null, GSTP1 1578A > G, NQO1 609C > T, MTHFR 677C > T, MTHFR 1298A > C, MTHFD1 1958G > A, 3'-TYMS 1494...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Child, Preschool
Share to Cohort Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Folic Acid

Share to Indonesia

Share to Infant

Share to Infant, Newborn

Share to Precursor Cell Lymphoblastic Leukemia-Lymphoma

Share to Xenobiotics

Source

Identifiers

PMID: 20824655
DOI: 10.1002/hon.965

Genes

MTHFR
TYMS
GSTP1
GSTT1
NQO1
GSTM1
MTHFD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Xenobiotic and folate pathway gene polymorphisms and risk of childhood acute lymphoblastic leukaemia in Javanese children.PMID 20824655Read ↗

Genetic susceptibility to childhood acute lymphoblastic leukemia shows protection in Malay boys: results from the Malaysia-Singapore ALL Study Group.Semantic proximity Read ↗

Gene polymorphisms in childhood ALLSemantic proximity Read ↗

Folate related gene polymorphisms and susceptibility to develop childhood acute lymphoblastic leukaemia.Semantic proximity Read ↗

5,10-Methylenetetrahydrofolate reductase polymorphisms and acute lymphoblastic leukemia risk: a meta-analysis.Semantic proximity Read ↗

Folate pathway gene polymorphisms, maternal folic acid use, and risk of childhood acute lymphoblastic leukemia.Semantic proximity Read ↗

The methylenetetrahydrofolate reductase 677T-1298C haplotype is a risk factor for acute lymphoblastic leukemia in children.Semantic proximity Read ↗

MTHFR-C677T Gene Polymorphism and Susceptibility to Acute Lymphoblastic Leukemia in Children: A Meta-Analysis.Semantic proximity Read ↗

Role of MTHFR genetic polymorphisms in the susceptibility to childhood acute lymphoblastic leukemia.Semantic proximity Read ↗

The association of folate pathway and DNA repair polymorphisms with susceptibility to childhood acute lymphoblastic leukemia.Semantic proximity Read ↗

Genetic polymorphisms and susceptibility to childhood acute lymphoblastic leukemia.Semantic proximity Read ↗

A meta-analysis of MTHFR C677T and A1298C polymorphisms and risk of acute lymphoblastic leukemia in children.Semantic proximity Read ↗

Maternal and offspring xenobiotic metabolism haplotypes and the risk of childhood acute lymphoblastic leukemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.