Article
Primary role of the HLA class II DRB1*0301 allele in Graves disease.
American journal of medical genetics - 18 Dec 2000
Zamani M, Spaepen M, Bex M, Bouillon R, Cassiman J J
Abstract excerpt
The association of the Graves disease (GD) with HLA DR3 and DQA1*0501 in Caucasians has been described previously. From these studies it could not be determined whether one specific locus was primarily involved. Using a case-control study design, we have examined the role of HLA class II gene polymorphisms in the predisposition for GD in a group of Belgian subjects. We demonstrated that both DRB1*0301 and...
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