Article
The pulmonary immune response of Balb/c mice vaccinated with the fusion protein of respiratory syncytial virus.
Vaccine - 1 Jan 1994
Hancock G E, Hahn D J, Speelman D J, Hildreth S W, Pillai S, McQueen K
Abstract excerpt
We have investigated the efficacy of vaccination with the purified fusion (F) protein of respiratory syncytial virus (RSV) on aluminium hydroxide adjuvant in Balb/c mice. The purpose of the study was to define the role of the local pulmonary mononuclear cell (PMC) infiltrate in the clearance of virus from the lower respiratory tract. Balb/c mice immunized with F protein were able to inhibit the replication of...
Topics
- Animals
- Antibodies, Viral
- CD8 Antigens
- Cells, Cultured
- Cytotoxicity, Immunologic
- Female
- HN Protein
- Immunity
- Immunotherapy, Adoptive
- Lung
- Mice
- Mice, Inbred BALB C
