Article
The interleukin 1 receptor antagonist gene allele 2 as a predictor of pouchitis following colectomy and IPAA in ulcerative colitis.
Gastroenterology - 1 Oct 2001
Carter M J, Di Giovine F S, Cox A, Goodfellow P, Jones S, Shorthouse A J, Duff G W, Lobo A J
Abstract excerpt
BACKGROUND & AIMS: The interleukin 1 receptor antagonist gene allele 2 has been suggested as a determinant of both disease susceptibility and extent in ulcerative colitis. The aim of this study was to assess the allele as a predictor of both the indication for colectomy and the occurrence of pouchitis after ileal pouch-anal anastomosis formation. METHODS: Genotyping for the +2018 single nucleotide polymorphism in...
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