Article
Interleukin-1 receptor antagonist gene polymorphism and rheumatoid arthritis.
Rheumatology international - 1 May 2004
Lee Young Ho, Kim Hyo Jin, Rho Young Hee, Choi Seong Jae, Ji Jong Dae, Song Gwan Gyu
Abstract excerpt
The aim of this study was to evaluate the association of polymorphism in IL-1 receptor antagonist (IL-1RA) gene intron 2 with susceptibility to rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) and their clinical features. Polymerase chain reaction of a genomic DNA was used to determine genotypes of the IL-1RA in 138 RA, 93 SLE, and 127 healthy control subjects. The frequency of IL-1RA allele 2...
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