Interleukin-1 receptor antagonist gene polymorphism and rheumatoid arthritis.

doi:10.1007/s00296-003-0337-9

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Article

Interleukin-1 receptor antagonist gene polymorphism and rheumatoid arthritis.

Rheumatology international - 1 May 2004

Lee Young Ho, Kim Hyo Jin, Rho Young Hee, Choi Seong Jae, Ji Jong Dae, Song Gwan Gyu

Abstract excerpt

The aim of this study was to evaluate the association of polymorphism in IL-1 receptor antagonist (IL-1RA) gene intron 2 with susceptibility to rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) and their clinical features. Polymerase chain reaction of a genomic DNA was used to determine genotypes of the IL-1RA in 138 RA, 93 SLE, and 127 healthy control subjects. The frequency of IL-1RA allele 2...

Topics

Adolescent
Adult
Aged
Arthritis, Rheumatoid
DNA
Female
Gene Frequency
Genetic Predisposition to Disease
Genotype
Humans
Interleukin 1 Receptor Antagonist Protein
Lupus Erythematosus, Systemic
Male
Middle Aged
Odds Ratio
Polymerase Chain Reaction
Polymorphism, Genetic
Sialoglycoproteins

Source

Open in PubMed

Identifiers

PMID: 14872281
DOI: 10.1007/s00296-003-0337-9

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