Article
Polymorphisms of the interleukin-1 gene cluster and ovarian cancer.
Journal of the Society for Gynecologic Investigation - 1 Jan 2000
Hefler Lukas A, Ludwig Elisabeth, Lebrecht Antje, Zeillinger Robert, Tong-Cacsire Dan, Koelbl Heinz, Leodolter Sepp, Tempfer Clemens B
Abstract excerpt
OBJECTIVE: Interleukin-1 (IL-1) is known to be critically involved in ovarian carcinogenesis. We investigated a panel of polymorphisms of the IL-1 and the IL-1 receptor antagonist (IL-1 RA) genes in patients with ovarian cancer. METHODS: One hundred thirty-four patients with surgically staged ovarian cancer, 27 patients with borderline ovarian cancer, and 134 healthy controls were genotyped for three...
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