Article
Interleukin 1 receptor antagonist (IL-1RA) polymorphism in women with cervical cancer.
Anticancer research - 1 Jan 2000
Mustea Alexander, Sehouli Jalid, Könsgen Dominique, Stengel Dirk, Sofroni Dumitru, Lichtenegger Werner
Abstract excerpt
BACKGROUND: Several studies suggest that immunological components play a key role in the development of cervical cancer. Polymorphism in the IL-1 RA gene was associated with various malignant diseases. Data is lacking for cervical cancer. MATERIALS AND METHODS: In a prospective study we analysed the polymorphism of IL-1RA in 113 women with cervical cancer and 107 with benign diseases. Genomic DNA fragments were...
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