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Article

Phosphorylation of beta-catenin at S33, S37, or T41 can occur in the absence of phosphorylation at T45 in colon cancer cells.

Cancer research - 1 Sept 2003

Wang Zhenghe, Vogelstein Bert, Kinzler Kenneth W

Abstract excerpt

Several previous studies in a variety of systems have suggested that phosphorylation at S45 of beta-catenin is essential for subsequent phosphorylation at more NH(2)-terminal residues. Using genetic models expressing beta-catenin under endogenous regulation, we find that phosphorylation of beta-catenin at S45 is not required for phosphorylation at residues S33, S37, or T41 in human colon cancer cells, in contrast...

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PMID: 14500351

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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