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Article

Point mutation in precore region of hepatitis B virus: sequential changes from 'wild' to 'mutant'.

Journal of gastroenterology and hepatology - 1 Jun 1996

Ehata T, Yokosuka O, Imazeki F, Omata M

Abstract excerpt

One point mutation to make a stop codon in the precore (pre-C) region of the hepatitis B virus DNA in anti-HBe-positive patients has been reported recently. This mutation disturbs the formation of the pre-C protein that is processed to make HBeAg. The relationship between the point mutation and HBe antigen antibody status was investigated in B-viral liver diseases. The pre-C region was amplified by a polymerase...

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Source

Identifiers

PMID: 8792312
DOI: 10.1111/j.1440-1746.1996.tb01704.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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