Mutations in the transcriptional regulatory region of the precore and core/pregenome of a hepatitis B virus with defective HBeAg production.

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Article

Mutations in the transcriptional regulatory region of the precore and core/pregenome of a hepatitis B virus with defective HBeAg production.

Fukuoka igaku zasshi = Hukuoka acta medica - 1 Nov 1994

Moriyama K, Takada T, Tsutsumi Y, Fukada K, Ishibashi H, Niho Y, Maeda Y

Abstract excerpt

Termination mutations in the precore open reading frame of hepatitis B virus (HBV) variants with defective hepatitis B e antigen (HBeAg) production have been demonstrated in both infected patients who have seroconverted to anti-HBe and those with fulminant hepatitis B. A donated plasma sample was...

Topics

Adult
Base Sequence
Codon
DNA, Viral
Female
Genome, Viral
Hepatitis B e Antigens
Hepatitis B virus
Humans
Molecular Sequence Data
Mutation
Regulatory Sequences, Nucleic Acid
Transcription, Genetic

Source

Open in PubMed

Identifiers

PMID: 7851832

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7851832-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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