Article
Biologic properties of hepatitis B viral genomes with mutations in the precore promoter and precore open reading frame.
Virology - 7 Jul 1997
Scaglioni P P, Melegari M, Wands J R
Abstract excerpt
It is now well recognized that mutations in the hepatitis B virus (HBV) genome occur during the natural course of chronic viral infection. Regions of the viral genome that are frequently affected by such mutations, rearrangements, and/or deletions generally involve the precore promoter, precore, and core as well as the preS gene regions. However, little is known regarding the biologic consequences of these...
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