Article
A short cis-acting sequence is required for hepatitis B virus pregenome encapsidation and sufficient for packaging of foreign RNA.
The EMBO journal - 1 Oct 1990
Junker-Niepmann M, Bartenschlager R, Schaller H
Abstract excerpt
The selective encapsidation of the hepadnaviral RNA pregenome from an excess of other viral and cellular mRNAs predicts specific protein-RNA interactions involving one or several sites on the pregenome. Using deletion analysis in a transient expression/packaging system in which all relevant viral...
Topics
- Base Sequence
- Capsid
- Cell Line
- Chromosome Deletion
- DNA, Viral
- Genes, Viral
- Genetic Vectors
- Hepatitis B virus
- Humans
- Models, Molecular
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- Protein Biosynthesis
- RNA Probes
- RNA, Viral
- Restriction Mapping
- Ribonucleases