Novel mutation in Hepatitis B virus preventing HBeAg production and resembling primate strains.

Abstract excerpt

Chronic carriers of hepatitis B infection often harbour virus strains with mutations in the precore region. These mutations are temporally associated with the development of HBeAg loss and seroconversion to anti-HBe. The most common precore mutation is a stop codon at position 1896, but other mutations leading to abolished HBeAg secretion have been described. Here, a novel precore mutation introducing a lysine in...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Carrier State
• Share to Hepatitis B
• Share to Hepatitis B Core Antigens