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Article

Abnormal kinetochore structure activates the spindle assembly checkpoint in budding yeast.

Molecular biology of the cell - 1 Aug 1996

Pangilinan F, Spencer F

Abstract excerpt

Saccharomyces cerevisiae cells containing one or more abnormal kinetochores delay anaphase entry. The delay can be produced by using centromere DNA mutations present in single-copy or kinetochore protein mutations. This observation is strikingly similar to the preanaphase delay or arrest exhibited in animal cells that experience spontaneous or induced failures in bipolar attachment of one or more chromosomes and...

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Identifiers

PMID: 8856664
DOI: 10.1091/mbc.7.8.1195
PMCID: PMC275972

Genes

BUB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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