Article
Abnormal kinetochore structure activates the spindle assembly checkpoint in budding yeast.
Molecular biology of the cell - 1 Aug 1996
Pangilinan F, Spencer F
Abstract excerpt
Saccharomyces cerevisiae cells containing one or more abnormal kinetochores delay anaphase entry. The delay can be produced by using centromere DNA mutations present in single-copy or kinetochore protein mutations. This observation is strikingly similar to the preanaphase delay or arrest exhibite...
Topics
- Anaphase
- Cell Cycle
- Centromere
- DNA, Fungal
- Genes, Fungal
- Kinetochores
- Molecular Structure
- Mutation
- Saccharomyces cerevisiae
- Spindle Apparatus
- Time Factors