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Article

A 40-kilodalton protein binds specifically to an upstream sequence element essential for muscle-specific transcription of the human myoglobin promoter.

Molecular and cellular biology - 1 Nov 1992

Bassel-Duby R, Hernandez M D, Gonzalez M A, Krueger J K, Williams R S

Abstract excerpt

To define transcriptional control elements responsible for muscle-specific expression of the human myoglobin gene, we performed mutational analysis of upstream sequences (nucleotide positions -373 to +7 relative to the transcriptional start site) linked to a firefly luciferase gene. Transient expression assays in avian and mammalian cells indicated that a CCCACCCCC (CCAC box) sequence (-223 to -204) is necessary...

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Identifiers

PMID: 1406677
DOI: 10.1128/mcb.12.11.5024-5032.1992
PMCID: PMC360435

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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