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Regulatory Elements Governing Transcription in Specialized Myofiber Subtypes

1 May 2001

Abstract excerpt

Skeletal myofibers of vertebrates acquire specialized metabolic and physiological properties as a consequence of developmental cues in the embryo and different patterns of contractile activity in the adult. The myoglobin gene is regulated stringently in muscle fibers, such that high myoglobin expression is observed in mitochondria-rich, oxidative myofibers (Types I and IIa) compared with glycolytic fibers (Type...

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PMID: 11279187
DOI: 10.1074/jbc.m101251200

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