Article
The basic region of myogenin cooperates with two transcription activation domains to induce muscle-specific transcription.
Molecular and cellular biology - 1 Jan 1992
Schwarz J J, Chakraborty T, Martin J, Zhou J M, Olson E N
Abstract excerpt
Myogenin is a skeletal muscle-specific transcription factor that can activate myogenesis when introduced into a variety of nonmuscle cell types. Activation of the myogenic program by myogenin is dependent on its binding to a DNA sequence known as an E box, which is associated with numerous muscle...
Topics
- Amino Acid Sequence
- Cell Differentiation
- Chimera
- DNA-Binding Proteins
- Fungal Proteins
- Gene Expression Regulation
- Hydrogen-Ion Concentration
- Molecular Sequence Data
- Muscle Proteins
- Muscles
- Mutation
- Myogenin
- Organ Specificity
- Saccharomyces cerevisiae Proteins
- Transcription Factors
- Transcription, Genetic