Human T-cell receptor V beta gene polymorphism and multiple sclerosis.

Article

Human T-cell receptor V beta gene polymorphism and multiple sclerosis.

American journal of human genetics - 1 Apr 1995

Wei S, Charmley P, Birchfield R I, Concannon P

Abstract excerpt

Population-based genetic associations have been reported between RFLPs detected with probes corresponding to the genes encoding the beta chain of the T-cell receptor for antigen (TCRB) and a variety of autoimmune disorders. In the case of multiple sclerosis (MS), these studies have localized a pu...

Topics

Adolescent
Adult
Alleles
Base Sequence
Child
Chromosome Mapping
Genetic Linkage
Humans
Middle Aged
Molecular Sequence Data
Multiple Sclerosis
Mutation
Polymerase Chain Reaction
Polymorphism, Genetic
Receptors, Antigen, T-Cell, alpha-beta

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