Article
Human T-cell receptor V beta gene polymorphism and multiple sclerosis.
American journal of human genetics - 1 Apr 1995
Wei S, Charmley P, Birchfield R I, Concannon P
Abstract excerpt
Population-based genetic associations have been reported between RFLPs detected with probes corresponding to the genes encoding the beta chain of the T-cell receptor for antigen (TCRB) and a variety of autoimmune disorders. In the case of multiple sclerosis (MS), these studies have localized a putative disease-associated gene to a region of approximately 110 kb in length, located within the TCRB locus. In the...
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