Article
Genetic variants in the tumor necrosis factor receptor II gene in patients with multiple sclerosis.
Tissue antigens - 1 Jan 2004
Ehling R, Gassner Ch, Lutterotti A, Strasser-Fuchs S, Kollegger H, Kristoferitsch W, Reindl M, Berger T
Abstract excerpt
Common genetic variants have been shown to influence disease susceptibility, disease course, or both in multiple sclerosis (MS). Several studies have suggested a role for tumor necrosis factor-alpha (TNF-alpha) in the pathogenesis of MS. Recently, it has been reported that the TNF receptor (TNFR) II plays an essential role in the pathology and progression of experimental autoimmune encephalomyelitis, an animal...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.