Article
Assignment of mutant tsN19 (complementation group E) of respiratory syncytial virus to the P protein gene.
The Journal of general virology - 1 Apr 1992
Caravokyri C, Zajac A J, Pringle C R
Abstract excerpt
The mutation responsible for the temperature-sensitive (ts) phenotype of mutant tsN19 (complementation group E) of respiratory syncytial virus has been located to the P protein gene. Viral protein synthesis was completely restricted at 39 degrees C, and the tsN19 P protein did not react with an anti-P monoclonal antibody (MAb) (3-5) at 33 degrees C. Reversion of temperature sensitivity restored reactivity with...
Topics
- Animals
- Antibodies, Monoclonal
- Antigens, Viral
- Base Sequence
- Cloning, Molecular
- DNA, Single-Stranded
- Epitopes
- Genes, Viral
- Genetic Complementation Test
- HN Protein
- Molecular Sequence Data
