Article
Premature stop codons in the G glycoprotein of human respiratory syncytial viruses resistant to neutralization by monoclonal antibodies.
Journal of virology - 1 Jun 1991
Rueda P, Delgado T, Portela A, Melero J A, García-Barreno B
Abstract excerpt
Mutants of human respiratory syncytial (RS) virus which escaped neutralization by monoclonal antibodies directed against the G glycoprotein were selected from the Long strain. Most mutants showed drastic antigenic changes, reflected in the lack of reactivity with several anti-G antibodies, includ...
Topics
- Antibodies, Monoclonal
- Codon
- Genes, Viral
- HN Protein
- Humans
- Mutation
- Neutralization Tests
- RNA, Messenger
- Respiratory Syncytial Viruses
- Viral Envelope Proteins
- Viral Proteins
