Article
Premature stop codons in the G glycoprotein of human respiratory syncytial viruses resistant to neutralization by monoclonal antibodies.
Journal of virology - 1 Jun 1991
Rueda P, Delgado T, Portela A, Melero J A, García-Barreno B
Abstract excerpt
Mutants of human respiratory syncytial (RS) virus which escaped neutralization by monoclonal antibodies directed against the G glycoprotein were selected from the Long strain. Most mutants showed drastic antigenic changes, reflected in the lack of reactivity with several anti-G antibodies, including the one used for selection. Sequence analysis revealed the presence of in-frame premature stop codons in the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
