Nucleotide sequence analysis of the respiratory syncytial virus subgroup A cold-passaged (cp) temperature sensitive (ts) cpts-248/404 live attenuated virus vaccine candidate.

doi:10.1006/viro.1996.0618

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Article

Nucleotide sequence analysis of the respiratory syncytial virus subgroup A cold-passaged (cp) temperature sensitive (ts) cpts-248/404 live attenuated virus vaccine candidate.

Virology - 15 Nov 1996

Firestone C Y, Whitehead S S, Collins P L, Murphy B R, Crowe J E

Abstract excerpt

The complete nucleotide sequence of the RSV cpts-248/404 live attenuated vaccine candidate was determined from cloned cDNA and was compared to that of the RSV A2/HEK7 wild-type, cold-passaged cp-RSV, and cpts-248 virus, which constitute the series of progenitor viruses. RSV cpts-248/404 is more a...

Topics

Animals
Cold Temperature
Humans
Mice
Molecular Sequence Data
Mutation
RNA, Viral
Respiratory Syncytial Viruses
Sequence Analysis
Temperature
Viral Vaccines

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