Monoallelic expression of the human H19 gene.

doi:10.1038/ng0492-40

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Article

Monoallelic expression of the human H19 gene.

Nature genetics - 1 Apr 1992

Zhang Y, Tycko B

Abstract excerpt

Monoallelic expression of several genes has been observed in mice in which transcripts from parental homologues are distinguishable, but this phenomenon has not been demonstrated in humans. One monoallelically expressed murine gene, H19, encodes an abundant fetal RNA. We have found restriction si...

Topics

Alleles
Base Sequence
Biological Evolution
Chromosomes, Human, Pair 11
DNA
Fetus
Gene Expression
Genetic Diseases, Inborn
Humans
Molecular Sequence Data
Neoplasms
Polymerase Chain Reaction
Polymorphism, Restriction Fragment Length
Restriction Mapping

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