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Article

The <i>H19</i> gene: regulation and function of a non-coding RNA

1 Jan 2006

Abstract excerpt

The H19 gene encodes a 2.3-kb non-coding mRNA which is strongly expressed during embryogenesis. This gene belongs to an imprinted cluster, conserved on mouse chromosome 7 and human chromosome 11p15. H19 is maternally expressed and the neighbouring Igf2 gene is transcribed from the paternal allele. These two genes are co-expressed in endoderm- and mesoderm-derived tissues during embryonic development, which...

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Identifiers

PMID: 16575179
DOI: 10.1159/000090831

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