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Article

Imprinted H19 gene expression in embryogenesis and human cancer: the oncofetal connection.

American journal of medical genetics - 6 Mar 2000

Ariel I, de Groot N, Hochberg A

Abstract excerpt

Cancer cells resemble embryonal cells morphologically and share with them characteristics such as reduced differentiation, rapid proliferation rate, and increased motility. Genes expressed in embryogenesis, down-regulated with tissue maturation and reexpressed in cancer, are designated as oncofetal genes, and many of them are used as tumor markers. The H19 gene is an imprinted gene that is expressed from the...

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Identifiers

PMID: 10751088
DOI: 10.1002/(sici)1096-8628(20000306)91:1<46::aid-ajmg8>3.0.co;2-i

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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