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Article

Analysis of p53 mutants for transcriptional activity.

Molecular and cellular biology - 1 Dec 1991

Raycroft L, Schmidt J R, Yoas K, Hao M M, Lozano G

Abstract excerpt

The wild-type p53 protein functions to suppress transformation, but numerous mutant p53 proteins are transformation competent. To examine the role of p53 as a transcription factor, we made fusion proteins containing human or mouse p53 sequences fused to the DNA binding domain of a known transcription factor, GAL4. Human and mouse wild-type p53/GAL4 specifically transactivated expression of a chloramphenicol...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 1944276
DOI: 10.1128/mcb.11.12.6067-6074.1991
PMCID: PMC361778

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Analysis of p53 mutants for transcriptional activity.PMID 1944276Read ↗

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