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Article

Nonrandom association between Huntington disease and two loci separated by about 3 Mb on 4p16.3.

Genomics - 1 Jun 1992

Andrew S, Theilmann J, Hedrick A, Mah D, Weber B, Hayden M R

Abstract excerpt

The gene for Huntington disease (HD) has been localized close to the telomere on the short arm of chromosome 4. However, refined mapping using recombinant HD chromosomes has resulted in conflicting findings and mutually exclusive candidate regions. Previously reported significant nonrandom allelic association between D4S95 and HD provided support for a more proximal location for the defective gene. In this paper,...

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Identifiers

PMID: 1351866
DOI: 10.1016/0888-7543(92)90246-o

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Nonrandom association between Huntington disease and two loci separated by about 3 Mb on 4p16.3.PMID 1351866Read ↗

Recombination of 4p16 DNA markers in an unusual family with Huntington disease.Semantic proximity Read ↗

Complex patterns of linkage disequilibrium in the Huntington disease region.Semantic proximity Read ↗

A linkage study with DNA markers (D4S95, D4S115, and D4S111) in Japanese Huntington disease families.Semantic proximity Read ↗

A recombination event that redefines the Huntington disease region.Semantic proximity Read ↗

Linkage disequilibrium and recombination make a telomeric site for the Huntington's disease gene unlikely.Semantic proximity Read ↗

New DNA markers in the Huntington's disease gene candidate region.Semantic proximity Read ↗

Delineation of a 50 kilobase DNA segment containing the recombination site in a sporadic case of Huntington's disease.Semantic proximity Read ↗

The Huntington's disease candidate region exhibits many different haplotypes.Semantic proximity Read ↗

Localization of the gene for a novel autosomal recessive neurodegenerative Huntington-like disorder to 4p15.3.Semantic proximity Read ↗

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group.Semantic proximity Read ↗

Non-random association between DNA markers and Huntington disease locus in the Italian population.Semantic proximity Read ↗

Huntington disease-linked locus D4S111 exposed as the alpha-L-iduronidase gene.Semantic proximity Read ↗

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