Nonrandom association between Huntington disease and two loci separated by about 3 Mb on 4p16.3.

doi:10.1016/0888-7543(92)90246-o

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Article

Nonrandom association between Huntington disease and two loci separated by about 3 Mb on 4p16.3.

Genomics - 1 Jun 1992

Andrew S, Theilmann J, Hedrick A, Mah D, Weber B, Hayden M R

Abstract excerpt

The gene for Huntington disease (HD) has been localized close to the telomere on the short arm of chromosome 4. However, refined mapping using recombinant HD chromosomes has resulted in conflicting findings and mutually exclusive candidate regions. Previously reported significant nonrandom alleli...

Topics

Alleles
Chromosome Mapping
Chromosomes, Human, Pair 4
DNA Probes
Genetic Markers
Haplotypes
Humans
Huntington Disease
Linkage Disequilibrium
Polymorphism, Restriction Fragment Length

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