A linkage study with DNA markers (D4S95, D4S115, and D4S111) in Japanese Huntington disease families.

doi:10.1007/BF01883710

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Article

A linkage study with DNA markers (D4S95, D4S115, and D4S111) in Japanese Huntington disease families.

The Japanese journal of human genetics - 1 Jun 1993

Watanabe M, Kondo I, Nissato S, Wakisaka A, Toda T, Ikeda J, Wasmuth J J, Gusella J F, Kanazawa I

Abstract excerpt

Attempts to isolate the Huntington disease (HD) gene based on its position have been frustrated by apparently contradictory recombination events in HD pedigrees that have predicted two non-overlapping candidate regions: 100 kb at the telomere of the short arm of chromosome 4, and a 2.2 Mb region...

Topics

Adult
Alleles
Asian People
Chromosome Mapping
Family Health
Genetic Linkage
Genetic Markers
Genome
Humans
Huntington Disease
Japan
Linkage Disequilibrium
Middle Aged
Polymorphism, Restriction Fragment Length

Source

Open in PubMed

Identifiers

PMID: 8102909
DOI: 10.1007/BF01883710

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8102909-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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