Article
New DNA markers in the Huntington's disease gene candidate region.
Somatic cell and molecular genetics - 1 Sept 1991
Lin C S, Altherr M, Bates G, Whaley W L, Read A P, Harris R, Lehrach H, Wasmuth J J, Gusella J F, MacDonald M E
Abstract excerpt
The search for the Huntington's disease (HD) gene has prompted construction of a complete long-range restriction map of a 2.5-Mb candidate region, distal to the DNA marker D4S10. To facilitate the procurement of cloned DNA from this candidate region, we have augmented the existing regional mappin...
Topics
- Alleles
- Cell Line
- Chromosome Deletion
- Chromosomes, Human, Pair 12
- Chromosomes, Human, Pair 4
- Cloning, Molecular
- Cosmids
- Electrophoresis, Gel, Pulsed-Field
- Genetic Markers
- Humans
- Huntington Disease
- Polymorphism, Restriction Fragment Length
- Restriction Mapping
- Translocation, Genetic