Recombination of 4p16 DNA markers in an unusual family with Huntington disease.

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Recombination of 4p16 DNA markers in an unusual family with Huntington disease.

American journal of human genetics - 1 Jun 1992

Pritchard C, Zhu N, Zuo J, Bull L, Pericak-Vance M A, Vance J M, Roses A D, Milatovich A, Francke U, Cox D R

Abstract excerpt

The Huntington disease (HD) mutation has been localized to human chromosome 4p16, in a 6-Mb region between the D4S10 locus and the 4p telomere. In a report by Robbins et al., a family was identified in which an affected individual failed to inherit three alleles within the 6-Mb region originating...

Topics

Adult
Alleles
Base Sequence
Blotting, Southern
Child
Chromosome Banding
Chromosomes, Human, Pair 4
DNA
Female
Genetic Markers
Genotype
Humans
Huntington Disease
Male
Molecular Sequence Data
Oligodeoxyribonucleotides
Pedigree
Polymerase Chain Reaction

Source

Open in PubMed Open full text

Identifiers

PMID: 1350884
PMCID: PMC1682573

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1350884-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics