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Article

Non-phenotypic selection of N-methyl-N-nitrosourea-induced mutations in human cells.

Nucleic acids research - 25 Mar 1992

Palombo F, Bignami M, Dogliotti E

Abstract excerpt

The distribution of mutations in a particular gene as detected by a selective mutation assay could be affected by the structural properties of the target protein. To investigate this, we have analysed N-methyl-N-nitrosourea (MNU)-induced mutations in two restriction recognition sequences of a target gene for mutation analysis and compared these data with what previously observed in a phenotypic mutation assay....

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Identifiers

PMID: 1348577
DOI: 10.1093/nar/20.6.1349
PMCID: PMC312182

Genes

GPT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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