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Article

Restriction fragment pattern analysis of HPRT mutations induced in rat-liver epithelial cells by alkylating and arylating agents.

Mutation research - 1 Feb 1992

Alvi N K, Williams G M

Abstract excerpt

Structural alterations in the hypoxanthine-guanine phosphoribosyl transferase (HPRT) gene in genomic DNA of adult rat-liver (ARL) epithelial cells that were mutated by alkylating and arylating mutagens were studied by restriction enzyme fragment pattern (RFP) analysis. ARL cells were mutated with the direct-acting alkylating agent N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) or the activation-dependent arylating...

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Source

Identifiers

PMID: 1370727
DOI: 10.1016/0027-5107(92)90057-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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